Livedoid skin reaction and mRNA Covid-19 vaccine: correspondence| Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology
Vol. 115: Issue 4 - August 2023
DOI: 10.32074/1591-951X-806
Letter to Editor
Published: 2023-09-14
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Livedoid skin reaction and mRNA Covid-19 vaccine: correspondence

Private Academic Consultant, Bangkok Thailand
handigarh University, Sahibzada Ajit Singh Nagar, Punjab, India

Article

Dear Editor,

we would like to share ideas on the publication “Livedoid skin reaction to 2nd dose of mRNA Covid-19 vaccine 1.” Girolami et al. observed that no cases of a livedoid skin reaction connected with the Covid-19 vaccine had been documented, and this case demonstrates that a huge livedoid reaction can be another type of skin reaction to the mRNA Covid-19 vaccine 1. Despite its benefits, the Covid-19 vaccine may be dangerous, which concerns us all. Because there is minimal information on the health and immunological status of vaccine recipients prior to inoculation, determining the precise etiology of a clinical problem may be difficult. A clinical comorbidity could be the source of the problem detected by the Covid-19 vaccine 2. For example, it is easy to misinterpret a clinical condition caused by infection in a vaccine recipient 2. It is now too early to identify any potential detrimental effects of the Covid-19 vaccination because there is no comprehensive, accurate record of a person’s health or immunological condition prior to receiving the immunization. Finally, it should be mentioned that the livedoid skin reaction may be observed in Covid-19 3. Asymptomatic Covid-19 is not uncommon and can occur at any moment, including during vaccination or after vaccination 4. As a result, this potential clinical entity must also be ruled out.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

FUNDING

None.

References

  1. Girolami I, Eisendle K, Kluge RW, Hanspeter E, Eccher A, Vizziello L, Zampieri P, Mazzoleni G. Livedoid skin reaction to 2nd dose of mRNA Covid-19 vaccine. Pathologica. 2022; 114:322-325. DOI
  2. Kebayoon A, Wiwanitkit V. Dengue After COVID-19 Vaccination: possible and Might be Missed. Clin Appl Thromb Hemost. 2021; 27:10760296211047229. DOI
  3. Ionescu MA. COVID-19 skin lesions are rarely positive at RT-PCR test: the macrophage activation with vascular impact and SARS-CoV-2-induced cytokine storm. Int J Dermatol. 2022; 61:3-6. DOI
  4. Joob B, Wiwanitkit V. Letter to the Editor: Coronavirus Disease 2019 (COVID-19), Infectivity, and the Incubation Period. J Prev Med Public Health. 2020; 53:70. DOI

Affiliations

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Rujittika Mungmunpuntipantip

Private Academic Consultant, Bangkok Thailand
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Viroj Wiwanitkit

handigarh University, Sahibzada Ajit Singh Nagar, Punjab, India
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License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright

© Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology , 2023

How to Cite

[1]
Mungmunpuntipantip, R. and Wiwanitkit, V. 2023. Livedoid skin reaction and mRNA Covid-19 vaccine: correspondence. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology. 115, 4 (Sep. 2023), 246. DOI:https://doi.org/10.32074/1591-951X-806.
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